Abstract:

The ability of an analytical method to measure R-LCM while also taking into account the presence of S-LCM is also crucial in the field of bioanalysis, which involves quantifying medication concentrations in biological samples. The development of new medicines or the evaluation of treatment outcomes can be jeopardized by inaccurate quantitative results from clinical trials. A reliable Liquid Chromatography-Mass Spectrometry (LC-MS) approach for the quantification of R-Lacosamide in the presence of S-Lacosamide is needed to solve these crucial difficulties. Improved knowledge of the pharmacokinetics and bioavailability of lacosamide will result from the application of such a technique, which will also aid in the quality control of lacosamide-containing medications. The ultimate goals of this study are to better care for patients, manage epilepsy and other neurological illnesses, and guarantee the safety and effectiveness of lacosamide-based medicines.

Description:

Ultra Performance, Liquid Chromatography, Thin Layer, pharmacokinetics, bioavailability, lacosamide-based medicines