ADVANCED HPLC METHOD FOR ACCURATE AND RAPID ANTIFUNGAL DRUG QUANTIFICATION

Authors:

T RAJENDRA PRASAD, DR. SHIRISH PREMCHAND JAIN

Page No: 751-756

Abstract:

The accurate quantification of antifungal drugs is crucial for both clinical applications and pharmaceutical development. High-performance liquid chromatography (HPLC) has emerged as one of the most reliable analytical techniques for the analysis of antifungal drugs due to its precision, sensitivity, and ability to handle complex samples. This paper explores the development and optimization of an advanced HPLC method for the rapid and accurate quantification of antifungal drugs. We evaluate the principles behind HPLC, discuss the selection of appropriate columns, mobile phases, and detection methods, and provide a detailed analysis of key factors such as resolution, accuracy, and precision. The proposed method demonstrates high efficiency and offers a valuable tool for the clinical and pharmaceutical analysis of antifungal agents.

Description:

.

Volume & Issue

Volume-12,ISSUE-12

Keywords

Fluconazole, Ketoconazole, Itraconazole, Amphotericin B, Gradient elution.